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KMID : 1024420210250040362
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Food Engineering Progress
2021 Volume.25 No. 4 p.362 ~ p.368
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The Effect of the Probiotics Mixture of Bifidobacterium Animalis ssp. Lactis and Lactobacillus rhamnosus on Obesity in High-Fat Diet-Induced Mice
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Kim Ha-Yoon
Kang Su-Min
Kim Hyun-Kyung
Kang Eun-Young
Go Gwang-Woong
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Abstract
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The prevalence of obesity is steadily growing worldwide, causing several severe complications, including type 2 diabetes and cardiovascular diseases. With the importance of preventive approaches to obesity, related nutraceuticals and compounds are developing. Probiotics are attracting attention as a substance that is effective against obesity. Among the probiotics, Lactobacillus rhamnosus Lb102 and Bifidobacterium animalis ssp. Bf141 individually has the effect of preventing metabolic syndrome, including anti-obesity. Therefore, we examined the effect of a mixture of Lactobacillus rhamnosus Lb102 and Bifidobacterium animalis ssp. Bf141. The mixture of Lactobacillus rhamnosus Lb102 (Lb102) and Bifidobacterium animalis ssp. Bf141 (Bf141) was administered to a high-fat diet (HFD, 60% kcal from fat)-induced obese mice for eight weeks. The probiotics mixture did not alter body weight, feed intake, and body adiposity, meaning the rescue of obesity was ineffective. Furthermore, there was no difference in the liver weight, which is the center of lipid synthesis. In addition, the probiotics mixture did not modify fecal lipid content, an indicator of lipid digestion and absorption. Serum triglycerides and total cholesterol levels also remained unchanged. In conclusion, these results imply that the probiotics mixture of Lb102 and Bf141 had no anti-obesity outcome in HFD-induced obese mice.
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KEYWORD
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Bifidobacterium animalis ssp. lactis Bf141, Lactobacillus rhamnosus Lb102, obesity, probiotics
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